Allelic structures and mechanisms of copy number change at the human DEFA1A3 copy number variable locus
The DEFA1A3 locus on human chromosome 8p23.1 exhibits extensive copy number variation; individuals have between 3-16 copies of DEFA1A3. The region has additional complexity in that each repeat unit contains a gene locus that can be occupied by one of two different genes, DEFA1 or DEFA3. These encode...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2014
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| Online Access: | https://eprints.nottingham.ac.uk/27737/ |