Base flipping in Tn10 transposition: an active flip and capture mechanism

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Base flipping in Tn10 transposition: an active flip and capture mechanism

The bacterial Tn5 and Tn10 transposases have a single active site that cuts both strands of DNA at their respective transposon ends. This is achieved using a hairpin intermediate that requires the DNA to change conformation during the reaction. In Tn5 these changes are controlled in part by a flippe...

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Bibliographic Details
Main Authors:	Bischerour, Julien, Chalmers, Ronald
Format:	Article
Published:	Public Library of Science 2009
Online Access:	https://eprints.nottingham.ac.uk/2772/

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