Base flipping in Tn10 transposition: an active flip and capture mechanism
The bacterial Tn5 and Tn10 transposases have a single active site that cuts both strands of DNA at their respective transposon ends. This is achieved using a hairpin intermediate that requires the DNA to change conformation during the reaction. In Tn5 these changes are controlled in part by a flippe...
| Main Authors: | , |
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| Format: | Article |
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Public Library of Science
2009
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| Online Access: | https://eprints.nottingham.ac.uk/2772/ |