Drug-targetting of duplex and quadruplex DNA

QR Code

Drug-targetting of duplex and quadruplex DNA

This thesis investigates structural and dynamic properties of drug recognition mechanisms to duplex and quadruplex DNA using primarily high field NMR techniques and molecular dynamics simulations. The mechanism of co-operative binding of Hoechst 33258 to the DNA minor groove of duplexes that contai...

Full description

Bibliographic Details
Main Author:	Gavathiotis, Evripidis
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2002
Online Access:	https://eprints.nottingham.ac.uk/27683/

Similar Items

Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs
by: Hirt, Bartholomäus V., et al.
Published: (2014)

Development of a series of bis-triazoles as G-quadruplex ligands
by: Saleh, Maysaa, et al.
Published: (2017)

Comparison Of Fab And Scfv Phage Display Efficiency: Application Of Best Format For The Development Of A Novel Dna G-Quadruplex Based Immunoassay
by: Loh, Qiuting
Published: (2015)

RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells
by: Lagah, Sunil, et al.
Published: (2014)

Fiber optic duplexer
by: O. S. Ali, Abu Baker
Published: (2006)

Bone drug targets
by: Dass, Crispin
Published: (2018)

Weldability of duplex stainless steel
by: Pramanik, Alokesh, et al.
Published: (2015)

Optical fibre duplexer module
by: Abdullah, Mohammad Khazani, et al.
Published: (2003)

Editorial: Current drug targets
by: Sulaiman, Ahmad Hatim, et al.
Published: (2019)

G-quadruplex microspheres-based optical RNA biosensor for arthropod-borne virus pathogen detection: A proof-of-concept with dengue serotype 2
by: Jamaluddin, Nur Diyana, et al.
Published: (2021)

Fiber optic duplexer module (FDM)
by: Abdullah, Mohamad Khazani
Published: (2005)

Processing of duplex stainless steel by WEDM
by: Pramanik, Alokesh, et al.
Published: (2018)

Weldability and machinability of duplex stainless steel
by: Pramanik, Alokesh, et al.
Published: (2015)

Kinase targets in CNS drug discovery
by: Gunosewoyo, Hendra, et al.
Published: (2017)

Duplex PCR assay for the species-specific detection of the marine pathogen, vibrio alginolyticus, using dnaJ and ompK genes
by: A. W., Nurul, et al.
Published: (2016)

Duplex surface treatment of steels by nitriding and chromizing
by: Hakami, F., et al.
Published: (2017)

Targeting DNA repair for personalisation of glioblastoma therapy
by: Perry, Christina Joy
Published: (2016)

Machinability study of first generation duplex (2205), second generation duplex (2507) and austenite stainless steel during drilling process
by: Nomani, J., et al.
Published: (2013)

Macromolecules as targeted drugs delivery vehicles: an overview
by: Ali, Yousaf, et al.
Published: (2019)

The therapeutic and psychosocial interaction in enhancing drug targets
by: Musa, Ramli, et al.
Published: (2018)

NMR Studies of Nucleic Acids as Drug Targets
by: Gallagher, Cathal T
Published: (2004)

Polyadenylation as a target for anti-inflammatory drugs
by: Radhi, Masar
Published: (2019)

Targeted bio-distribution of drugs to the lymphatic system
by: Jewell, Adelaide
Published: (2022)

In-silico drug target design & its approaches
by: Abduallah Alsafi, Hassen Mohammed, et al.
Published: (2011)

Design And Development Of Simplex-To-Full Duplex Converter (Sfdc)
by: Abas @ Ismail, Ahmad Fauzi
Published: (2002)

Bluetooth transceivers for full duplex communications in mobile robots
by: Choo, S. H., et al.
Published: (2002)

Corrosion behavior of duplex stainless steel in sea water
by: -, Suryanto
Published: (2011)

Fairness Considerations in Full-Duplex MIMO Interference Channels
by: Cirik, A., et al.
Published: (2015)

DNA repair in cancer: emerging targets for personalized therapy
by: Abbotts, Rachel, et al.
Published: (2014)

Target DNA recognition using electrochemical impedance spectroscopy
by: Michaels, P., et al.
Published: (2010)

Structure, dynamics and hydration in drug-DNA recognition
by: Williams, Huw Edward Llewelyn
Published: (2001)

Helicobacter pylori biomimics for gastric-targeted drug delivery
by: Hage, N.
Published: (2016)

Development of an EGFR-targeted Drug Delivery System for Glioblastoma
by: Zhao, Zi-Ruo
Published: (2023)

Hardfacing of duplex stainless steel using melting and diffusion processes
by: H, Lailatul, et al.
Published: (2017)

Optimization of surface roughness on duplex stainless steel in dry milling
by: Nurul Hidayah, Razak, et al.
Published: (2024)

Space division duplex (SDD) system using smart antenna
by: Ng, Chee Kyun, et al.
Published: (2005)

Throughput analysis of full-duplex communication cognitive radio network
by: Lodro, Mir Muhammad, et al.
Published: (2017)

Investigating the Anisotropic Behaviour of Lean Duplex Stainless Steel 2101
by: Ameri, Ali Abbas Hussei, et al.
Published: (2017)

Strain rate effect on the mechanical response of duplex stainless steel
by: Ameri, A., et al.
Published: (2018)

Targeting DNA repair and hypoxia to improve radioresponse in breast cancer
by: Aiyappa, Radhika
Published: (2020)