Alkaloid inspired spirocyclic oxindoles from 1,3-dipolar cycloaddition of pyridinium ylides

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Alkaloid inspired spirocyclic oxindoles from 1,3-dipolar cycloaddition of pyridinium ylides

Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles that proceed in high yield and with very good regio- and diastereoselectivity are reported. The resulting cycloadducts have the same stereochemistry of biologically active oxindole alkaloids, such as strychnofoline.

Bibliographic Details
Main Authors:	Day, Jonathan, Uroos, Maliha, Castledine, Richard A., Lewis, William, McKeever-Abbas, Ben, Dowden, James
Format:	Article
Published:	Royal Society of Chemistry 2013
Online Access:	https://eprints.nottingham.ac.uk/2738/

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