Alkaloid inspired spirocyclic oxindoles from 1,3-dipolar cycloaddition of pyridinium ylides
Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles that proceed in high yield and with very good regio- and diastereoselectivity are reported. The resulting cycloadducts have the same stereochemistry of biologically active oxindole alkaloids, such as strychnofoline.
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Royal Society of Chemistry
2013
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| Online Access: | https://eprints.nottingham.ac.uk/2738/ |