Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health

Interleukin 1β (IL-1β) and tumor necrosis factor α (TNF-α) are key cytokines that drive the production of inflammatory mediators and matrix-degrading enzymes in osteoarthritis (OA). These proinflammatory cytokines bind to their respective cell surface receptors and activate inflammatory signaling pa...

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Bibliographic Details
Main Authors: Mobasheri, Ali, Henrotin, Yves, Biesalski, Hans-Konrad, Shakibaei, Mehdi
Format: Article
Published: MDPI 2012
Online Access:https://eprints.nottingham.ac.uk/2702/