Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β
Introduction: Arthritic diseases are characterized by the degradation of collagenous and noncollagenous extracellular matrix (ECM) components in articular cartilage. The increased expression and activity of matrix metalloproteinases (MMPs) is partly responsible for cartilage degradation. This study...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
BioMed Central
2013
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| Online Access: | https://eprints.nottingham.ac.uk/2701/ |