5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development

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5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development

5-hydroxymethyl-cytosine (5-hmc) is a cytosine modification that is relatively abundant in mammalian pre-implantation embryos and embryonic stem cells (Esc) derived from mammalian blastocysts. Recent observations imply that both 5-hmc and Tet1/2/3 proteins, catalyzing the conversion of 5-methyl-...

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Bibliographic Details
Main Authors:	Almeida, Rimple D., Loose, Matthew, Sottile, Virginie, Matsa, Elena, Denning, Chris, Young, Lorraine, Johnson, Andrew D., Gering, Martin, Ruzov, Alexey
Format:	Article
Published:	Landes Bioscience 2012
Online Access:	https://eprints.nottingham.ac.uk/2698/

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