5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development
5-hydroxymethyl-cytosine (5-hmc) is a cytosine modification that is relatively abundant in mammalian pre-implantation embryos and embryonic stem cells (Esc) derived from mammalian blastocysts. Recent observations imply that both 5-hmc and Tet1/2/3 proteins, catalyzing the conversion of 5-methyl-...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Published: |
Landes Bioscience
2012
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| Online Access: | https://eprints.nottingham.ac.uk/2698/ |