Adenosine-A3 receptors in neutrophil microdomains
promote the formation of bacteria-tethering cytonemes

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Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes

The A3‐adenosine receptor (A3AR) has recently emerged as a key regulator of neutrophil behaviour. Using a fluorescent A3AR ligand, we show that A3ARs aggregate in highly polarized immunomodulatory microdomains on human neutrophil membranes. In addition to regulating chemotaxis, A3ARs promote the for...

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Bibliographic Details
Main Authors:	Corriden, Ross, Self, Tim, Akong-Moore, Kathryn, Nizet, Victor, Kellam, Barrie, Briddon, Stephen J., Hill, Stephen J.
Format:	Article
Published:	Nature Publishing Group 2013
Online Access:	https://eprints.nottingham.ac.uk/2675/

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