Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes
The A3‐adenosine receptor (A3AR) has recently emerged as a key regulator of neutrophil behaviour. Using a fluorescent A3AR ligand, we show that A3ARs aggregate in highly polarized immunomodulatory microdomains on human neutrophil membranes. In addition to regulating chemotaxis, A3ARs promote the for...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Published: |
Nature Publishing Group
2013
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| Online Access: | https://eprints.nottingham.ac.uk/2675/ |