Activation of store-operated calcium entry in airway smooth muscle cells: insight from a mathematical model

Intracellular dynamics of airway smooth muscle cells (ASMC) mediate ASMC contraction and proliferation, and thus play a key role in airway hyper-responsiveness (AHR) and remodelling in asthma. We evaluate the importance of store-operated entry (SOCE) in these dynamics by constructing a mathematic...

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Bibliographic Details
Main Authors: Croisier, Huguette, Tan, Xiahui, Perez-Zoghbi, Jose F., Sanderson, Michael J., Sneyd, James, Brook, Bindi S.
Format: Article
Published: Public Library of Science 2013
Online Access:https://eprints.nottingham.ac.uk/2584/