Helicobacter pylori down-regulates expression of human ß-defensin 1 in the gastric mucosa in a type IV secretion dependent fashion
Helicobacter pylori establishes a chronic lifelong infection in the human gastric mucosa, which may lead to peptic ulcer disease or gastric adenocarcinoma. The human beta-defensins (hβDs) are antimicrobial peptides, hβD1 being constitutively expressed in the human stomach. We hypothesized that H. py...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Published: |
Wiley
2013
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| Online Access: | https://eprints.nottingham.ac.uk/2410/ |