A practical drug discovery project at the undergraduate level

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A practical drug discovery project at the undergraduate level

A practical drug discovery project for third-year undergraduates is described. No previous knowledge of medicinal chemistry is assumed. Initial lecture-workshops cover the basic principles; then students are asked to improve the profile of a weakly potent, poorly soluble PI3K inhibitor (1). Comp...

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Bibliographic Details
Main Authors:	Fray, Michael J., Macdonald, Simon J.F., Baldwin, Ian R., Barton, Nick, Brown, Jack, Campbell, Ian B., Churcher, Ian, Coe, Diane M., Cooper, Anthony W.J., Craven, Andrew P., Fisher, Gail, Inglis, Graham G.A., Kelly, Henry A., Liddle, John, Maxwell, Aoife C., Patel, Vipulkumar K., Swanson, Stephen, Wellaway, Natalie
Format:	Article
Published:	Elsevier 2013
Subjects:	undergraduate research project asthma kinase PI3K delta thienopyrimidines
Online Access:	https://eprints.nottingham.ac.uk/2292/

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