Dendritic cable with active spines: a modeling study in the spike-diffuse-spike framework

The spike-diffuse-spike (SDS) model describes a passive dendritic tree with active dendritic spines. Spine-head dynamics is modelled with a simple integrate-and-fire process, whilst communication between spines is mediated by the cable equation. Here we develop a computational framework that allows...

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Bibliographic Details
Main Authors: Timofeeva, Yulia, Lord, Gabriel, Coombes, Stephen
Format: Article
Published: 2005
Subjects:
Online Access:https://eprints.nottingham.ac.uk/210/