Subcellular calcium dynamics in a whole-cell model of an atrial myocyte

In this study, we present an innovative mathematical modeling approach that allows detailed characterization of Ca(2+) movement within the three-dimensional volume of an atrial myocyte. Essential aspects of the model are the geometrically realistic representation of Ca(2+) release sites and physiolo...

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Bibliographic Details
Main Authors: Thul, Ruediger, Coombes, Stephen, Roderick, H. Llewelyn, Bootman, Martin D.
Format: Article
Published: National Academy of Sciences 2012
Online Access:https://eprints.nottingham.ac.uk/1761/