Analysis of the canonical initiation and trans-acting factor requirements of 5'TOP containing mRNAs

All eukaryotic mRNAs process a cap structure (m7G(5')ppp(5')N) at the S' end of their message and most have an A as the first nucleotide after the cap. However, 30% of messages within eukaryotic cells have a C (m7G(t')ppp(5')C) as the first nucleotide followed by a short pol...

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Bibliographic Details
Main Author: Garside, Paul
Format: Thesis (University of Nottingham only)
Language:English
Published: 2010
Online Access:https://eprints.nottingham.ac.uk/14089/