Investigation of the epitope specificities of antibodies to islet β-cell autoantigens

QR Code

Investigation of the epitope specificities of antibodies to islet β-cell autoantigens

Glutamic acid decarboxylase-65 (GAD-65) and the tyrosine phosphatase-like protein IA-2 are major targets of autoimmunity in type I diabetes mellitus (type I DM), stiff-man syndrome (SMS) and autoimmune polyendocrine syndrome (APS). In this study, the precise epitopes in GAD-65 of three different mou...

Full description

Bibliographic Details
Main Author:	Al-bukhari, Talat Abdullah
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2001
Subjects:	Antigenic determinants Epitope mapping Type 1 diabetes mellitus GAD-65 Autoantigens Monoclonal antibodies
Online Access:	https://eprints.nottingham.ac.uk/13868/

Similar Items

The generation and characterisation of anti-glycan monoclonal antibodies
by: Chua, Jia Xin
Published: (2017)

The Regulation of Peptide Mimotope/Epitope Recognition by Monoclonal Antibodies
by: Smith, Richard Gary
Published: (2002)

Analysis of candidate retinal autoantigens in autoimmune uveitis
by: Morgan, James
Published: (2005)

Development of monoclonal antibodies against porcine blood for detection in fish-based products
by: Raja Nhari, Raja Mohd Hafidz
Published: (2017)

Localization of the antigenic sites of Newcastle disease virus nucleocapsid using a panel of monoclonal antibodies
by: Ahmad-Raus, Raha, et al.
Published: (2009)

Production and evaluation of monoclonal antibody against Strongyloides ratti
by: Aliyu, Mahmuda
Published: (2017)

Penghasilan Hibridoma yang Merembeskan Antibodi Monoklon Terhadap Hormon Tiroksin (T4)
by: Yahya, Siti Romlah
Published: (1994)

Generation of human monoclonal antibodies: the development of methods to identify and isolate neutralising antibodies targeted to Ebolavirus from peripheral blood
by: Bailey, Graham D.
Published: (2017)

Production, characterization and scaling up of monoclonal antibodies against neuraminidase glycoprotein of avian influenza virus subtype H9N2
by: Abdelaziz Fadul, Sana Awad
Published: (2011)

Characterization of M1A2 monoclonal antibody and in vitro cytotoxicity assessment
by: Bashokouh, Fatemeh
Published: (2012)

TANTIGEN 2.0: a knowledge base of tumor T cell antigens and epitopes
by: Zhang, Guanglan, et al.
Published: (2021)

Optimization of serum free medium for the production of humanized anti-cea monoclonal antibody.
by: Ab Latif, Nurzila
Published: (2011)

Analysis of g s-transferase, protien tyrosine phosphatase 1B, nuclear factor kappa-B1 and leptin receptor genetic polymorphisms as risk factors for Malaysian type 2 diabetes mellitus subjects
by: Etemad, Ali
Published: (2013)

Predicting response to monoclonal antibody in severe asthma
by: Pang, Yik Lam
Published: (2022)

Suppression of apoptosis in perfusion culture of Myeloma NS0 cells enhances cell growth but reduces antibody productivity
by: Tey, Beng Ti, et al.
Published: (2004)

A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of 1- adrenoceptors expressed in stable cell lines
by: Soave, Mark, et al.
Published: (2018)

Hepatitis B Core Particle as a Display Platform for Foreign Epitopes
by: Yap, Wei Boon
Published: (2011)

Chimeric T7 bacteriophage particles displaying VP1 epitopes as a diagnostic tool detecting foot-and-mouth disease virus antibodies in bovine serum samples
by: Wong, Chuan Loo
Published: (2019)

Factors associated with glycaemic control among diabetes mellitus type 2 patients attending health clinics in Tampin district Negeri Sembilan, Malaysia
by: Wan Hamdzan, Wan Farzana Fasya
Published: (2016)

Characterisation of monoclonal antibodies specific for hamster leukocyte differentiation molecules
by: Rees, Jennifer, et al.
Published: (2016)

Association of dietary patterns with socio-demographic, lifestyle, weight status and biochemical profiles among type 2 diabetes mellitus patients in a special Medical Center, Tehran Iran
by: Zad, Nasrin Darani
Published: (2012)

The interface between adaptive and innate neutralisation of virus entry: competition, addition or synergy?
by: Wartnaby, Sophie R.
Published: (2023)

Penghasilan Sel Hibridoma Menggunakan Teknik Elektrofusion
by: Hamid, Muhajir
Published: (1995)

Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease
by: Shindi, Reham, et al.
Published: (2017)

Production, Establishment and Characterisation of Monoclonal Antibody Against Breast Cancer Cell Line (Mcf-7)
by: Ong, Boo Kean
Published: (1995)

Effects of Antioxidant Vitamin C, E and C+E Supplementation on Plasma Lipid Profiles, Glycemic Control, and Antioxidant Status Among Type 2 Diabetes Mellitus Subjects in Tehran, Iran
by: Rafighi, Zahra
Published: (2011)

Analysis of gastrointestinal microbiota in relation to obesity and type 2 diabetes among adults
by: Kaliyappan, Roseni
Published: (2015)

Correlation of vitamin D and E plasma levels with the pathophysiology of type 2 diabetes mellitus among adults in Selangor, Malaysia
by: Md Razip, Nurliyana Najwa
Published: (2018)

Effectiveness of practice guidelines nutritional care and basic nutritional care on anthropometric and metabolic outcomes in type 2 diabetes mellitus patients at Sultan Qaboos University Hospital, Oman
by: Al-Shookri, Ali Obaid Salim
Published: (2013)

Factors associated with glycemic status among type 2 diabetes mellitus patients in Merjan Diabetic Centre, Iraq
by: Al Hasnawi, Ali Kadhim Abbood
Published: (2015)

Factors associated with level of glycaemic control among type 2 diabetes mellitus patients in selected health clinics in Kuala Selangor, Malaysia
by: Abdullah, Nurul Ain
Published: (2018)

Analysis of genetic polymorphism as risk factor of diabetes nephropathy among type 2 diabetic patients of a tertiary hospital
by: Yahya, Mohd Jokha
Published: (2017)

Effectiveness of a nurse-led diabetes self-management education on glycosylated hemoglobin among Iranian adults with type 2 diabetes
by: Azami, Golnaz
Published: (2019)

Metabolic effects of Cosmos caudatus Kunth (ulam raja) supplementation in type-2 diabetes mellitus patients
by: Cheng, Shi Hui
Published: (2017)

Expression profiling of genes related to endothelial cell function in pre-diabetes and type 2 diabetes subjects
by: Moradipoor, Sara
Published: (2016)

Factors associated with adequate health literacy among type 2 diabetes mellitus patients attending rural government health clinics in Kuala Selangor, Malaysia
by: Shaharudin, Noor Amanina
Published: (2018)

SLC22A1, SLC22A2, SLC22A3 and 11ßHSD1 gene polymorphisms among Malaysian Indians with type 2 diabetes mellitus
by: Abood, Al Ashoor Sabah Ghasan
Published: (2019)

Factors of medication non-adherence among type 2 diabetes mellitus patients in Malaysian public hospitals
by: Abdullah, Nor Fadhilah
Published: (2020)

An investigation into the vaccine responsiveness of multiple sclerosis patients being treated with Ocrelizumab
by: Thomas, Niamh
Published: (2024)

Faktor Determinan Kesihatan Terhadap Pengawalan Diabetes dalam Kalangan Pesakit Diabetes Jenis 2 di Klinik Kesihatan Bandar Tun Razak, Kuala Lumpur
by: Ismail, Hasimah
Published: (2010)