Investigation of the epitope specificities of antibodies to islet β-cell autoantigens

Glutamic acid decarboxylase-65 (GAD-65) and the tyrosine phosphatase-like protein IA-2 are major targets of autoimmunity in type I diabetes mellitus (type I DM), stiff-man syndrome (SMS) and autoimmune polyendocrine syndrome (APS). In this study, the precise epitopes in GAD-65 of three different mou...

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Bibliographic Details
Main Author: Al-bukhari, Talat Abdullah
Format: Thesis (University of Nottingham only)
Language:English
Published: 2001
Subjects:
Online Access:https://eprints.nottingham.ac.uk/13868/