Proteomics of mouse cortex following conditional deletion of Psmc1 proteasomal subunit in neurones

Neurodegenerative diseases are characterized by progressive degeneration of selective neurones in the nervous system and the formation of protein inclusions in surviving neurones. The mechanisms underlying neurodegeneration and neuroprotection in the nervous system remain elusive. Ubiquitin is one o...

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Bibliographic Details
Main Author: Elkharaz, Jamal Ibrahim
Format: Thesis (University of Nottingham only)
Language:English
Published: 2013
Online Access:https://eprints.nottingham.ac.uk/13712/