A human alpha-arrestin protein with a potential role in cargo protein trafficking within the endocytic system

β-Arrestins are essential adaptors for G protein-coupled receptor (GPCR) trafficking. Evolutionary ancestors of the β-arrestins – dubbed α-arrestins – are present in yeast/fungi and, similar to β-arrestins, recognise cargo proteins and mediate their intracellular trafficking. Mammalian α-arrestins i...

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Bibliographic Details
Main Author: Lake, David Jonathan
Format: Thesis (University of Nottingham only)
Language:English
Published: 2013
Online Access:https://eprints.nottingham.ac.uk/13335/