Using the Cre/loxP recombination system to study the role of the PI3K/AKT signalling transduction pathway and the embryonic cellular origin of adult haematopoietic stem cells in the zebrafish

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Using the Cre/loxP recombination system to study the role of the PI3K/AKT signalling transduction pathway and the embryonic cellular origin of adult haematopoietic stem cells in the zebrafish

Haematopoietic stem cells (HSCs) are present in the bone marrow (BM) and maintain our blood system throughout life. These cells have clinical importance and their transplantation constitutes the most common type of stem cell therapy available. Lack of BM donors and our inability to expand HSCs ex vi...

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Bibliographic Details
Main Author:	Jalali, Maryam
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2013
Online Access:	https://eprints.nottingham.ac.uk/12999/

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