Using the Cre/loxP recombination system to study the role of the PI3K/AKT signalling transduction pathway and the embryonic cellular origin of adult haematopoietic stem cells in the zebrafish
Haematopoietic stem cells (HSCs) are present in the bone marrow (BM) and maintain our blood system throughout life. These cells have clinical importance and their transplantation constitutes the most common type of stem cell therapy available. Lack of BM donors and our inability to expand HSCs ex vi...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2013
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| Online Access: | https://eprints.nottingham.ac.uk/12999/ |