Design and synthesis of protein arginine methyltransferase inhibitors

Biological methylation is defined as the transfer of a methyl group from S-adenosyl-L-methionine(SAM) to one of a wide range of potential acceptors such as DNA, RNA, protein, hormones and neurotransmitters. Protein arginine methylation is a common post-translational modification facilitated by prote...

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Bibliographic Details
Main Author: Hong, Wei
Format: Thesis (University of Nottingham only)
Language:English
Published: 2010
Online Access:https://eprints.nottingham.ac.uk/12835/