The role of the cholecystokinin 2 receptor in cancer

The gastrointestinal (GI) hormone, gastrin, promotes cancer progression and its down-regulation has been linked to reduced cancer stem cell numbers. Gastrin acts through the cholecystokinin-2 receptor (CCK-2R) and its biological effects are blocked by CCK-2R inhibitors. We investigated the regulatio...

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Bibliographic Details
Main Author: Mayne, Cerys Mary
Format: Thesis (University of Nottingham only)
Language:English
English
Published: 2011
Online Access:https://eprints.nottingham.ac.uk/12705/