The induction and effects of Substance P and its receptor in human immune cells and neurons: potential relevance in multiple sclerosis

INTRODUCTION: Substance P (SP) has well-established roles in neurogenic inflammation and pain transmission, however recently, a number of SP immunomodulatory effects have been shown. In this thesis SP and its neurokinin-1-receptor (NK1R) role in autoimmune inflammation was investigated with an appli...

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Bibliographic Details
Main Author: Vilisaar, Janek
Format: Thesis (University of Nottingham only)
Language:English
Published: 2012
Subjects:
Online Access:https://eprints.nottingham.ac.uk/12663/