Genetic and functional characterisation of the LIMD1 promoter and gene product: from lung cancer to the hypoxic response

LIM domain containing protein 1 (LIMD1) is a tumour suppressor located at 3p21.3, a region that harbours multiple tumour suppressor genes and is commonly subject to homozygous deletions and loss of heterozygosity in many cancers. The mechanism of LIMD1 tumour suppressive activities are not fully elu...

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Bibliographic Details
Main Author: Foxler, Daniel
Format: Thesis (University of Nottingham only)
Language:English
Published: 2012
Online Access:https://eprints.nottingham.ac.uk/12604/