Structure, dynamics and hydration in drug-DNA recognition

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Structure, dynamics and hydration in drug-DNA recognition

The role of deoxyribonucleic acids in the cell has made DNA an attractive target for drug molecules. The anthracycline antitumour antibiotics are potent cytotoxic agents that have found widespread use in cancer chemotherapy. Nogalamycin binds DNA through intercalation, preferentially to 5'-TpG...

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Bibliographic Details
Main Author:	Williams, Huw Edward Llewelyn
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2001
Online Access:	https://eprints.nottingham.ac.uk/12452/

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