Structure, dynamics and hydration in drug-DNA recognition
The role of deoxyribonucleic acids in the cell has made DNA an attractive target for drug molecules. The anthracycline antitumour antibiotics are potent cytotoxic agents that have found widespread use in cancer chemotherapy. Nogalamycin binds DNA through intercalation, preferentially to 5'-TpG...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2001
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| Online Access: | https://eprints.nottingham.ac.uk/12452/ |