Mathematical modelling of telomere dynamics

Telomeres are repetitive elements of DNA which are located at the ends of chromosomes. During cell division, telomeres on daughter chromomeres shorten until the telomere length falls below a critical level. This shortening restricts the number of cell divisions. In this thesis, we use mathematical m...

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Bibliographic Details
Main Author: Qi, Qi
Format: Thesis (University of Nottingham only)
Language:English
Published: 2011
Online Access:https://eprints.nottingham.ac.uk/12258/