Molecular evolution of the def6/swap70 gene family and functional analysis of swap70a in zebrafish embryogenesis
Rho GTPases including Rac1, RhoA, and Cdc42 are molecular switches as for signal transduction. Cycling between the GTP-bound active state and GDPbound inactive state is tightly controlled by regulatory proteins. The exchange of GDP for GTP is catalysed by guanine nucleotide exchange factors (GEFs)....
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2010
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| Online Access: | https://eprints.nottingham.ac.uk/11681/ |