Dissecting protein-protein interactions facilitating secretion of the virulence factor EspC by enteropathogenic Escherichia coli

This study investigates the domain structure and secretion of the autotransporter (AT) EspC, secreted by enteropathogenic Escherichia coli (EPEC). The boundaries of the archetypical signal peptide and beta-domain surrounding the passenger domain of EspC were established. Then, structural modelling w...

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Bibliographic Details
Main Author: Bishop, Keith
Format: Thesis (University of Nottingham only)
Language:English
Published: 2009
Subjects:
Online Access:https://eprints.nottingham.ac.uk/11023/