Testing for partial agonism of the aryl hydrocarbon receptor

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is the most potent of a group of persistent organic pollutants (POPs). The aryl hydrocarbon receptor (AhR) has a high affinity for these dioxin-like compounds with activation increasing transcription of CYP1A1. The aim of this paper was to measure the agoni...

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Bibliographic Details
Main Author: Wall, Richard J.
Format: Thesis (University of Nottingham only)
Language:English
Published: 2008
Online Access:https://eprints.nottingham.ac.uk/11002/