The role of PPARa in Cytochrome P450 gene expression and DNA synthesis
Cytochrome family P450 4A encode a major group of enzymes which are involved in the mechanism of peroxisome proliferation in rodents. Induction of CYP4A expression by peroxisome proliferators is due to transcriptional activation, mediated via the peroxisome proliferator activated receptor alpha. Cyp...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2001
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| Online Access: | https://eprints.nottingham.ac.uk/10402/ |