The development of novel solid phase methodologies for the synthesis of atypical peptides and non-peptide entities

Solid phase peptide synthesis (SPPS) of branched/cyclic peptides, multiple antigenic peptides (MAPs), pseudopeptide toxins etc. requires amine protection orthogonal to the established Fmoc/Boc protocols. It was envisaged that progression from Dde to N-1-(4-Nitro-l,3-dioxoindan-2-ylidene)ethyl (Nde)...

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Bibliographic Details
Main Author: Kellam, Barrie
Format: Thesis (University of Nottingham only)
Language:English
Published: 1996
Online Access:https://eprints.nottingham.ac.uk/10381/