Cytochrome P450-mediated metabolism and cytotoxicity in rat cultured hepatocytes

The aim of this investigation was to define the in vitro conditions necessary to support cytochrome P450-mediated metabolism in rat cultured hepatocytes, such that this system could then be used as an in vitro model in the study of cytochrome P450-mediated cytotoxicity. Maintenance of P450-dependen...

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Bibliographic Details
Main Author: Hammond, Alison H.
Format: Thesis (University of Nottingham only)
Language:English
Published: 1990
Online Access:https://eprints.nottingham.ac.uk/10337/