Development of Cancer Immunotherapeutics Targeting Complement Regulatory Protein CD55

CD55 is one of the complement regulatory/inhibitory proteins and is over-expressed on a wide range of solid tumours. CD55 is also known to be deposited within tumour stroma and is secreted in an active soluble form, mediated by matrix metalloproteinase-7. The complement cascade forms part of the i...

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Bibliographic Details
Main Author: Bradley, Richard Grayson
Format: Thesis (University of Nottingham only)
Language:English
Published: 2007
Subjects:
Online Access:https://eprints.nottingham.ac.uk/10258/