AFM investigations of critical interactions in the Bacillus primosome and Cryogenic AFM a new tool for structural biology

In this thesis for the first AFM has been employed for the high resolution imaging of a protein assembly. The DnaB-DnaG Helicase-Primase interaction in Bacillus is the key reaction that causes the switch from primase mode to polymerisation mode. This assembly was imaged using the AFM to a sub-mole...

Full description

Bibliographic Details
Main Author: Turner, Ian James
Format: Thesis (University of Nottingham only)
Language:English
Published: 2006
Subjects:
Online Access:https://eprints.nottingham.ac.uk/10188/