Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico approach

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Screening of high-risk deleterious missense variations in the CYP1B1 gene implicated in the pathogenesis of primary congenital glaucoma: A comprehensive in silico approach

Background Primary congenital glaucoma (PCG) is the most common subtype of glaucoma caused by defects in the cytochrome P450 1B1 (CYP1B1) gene. It is developing among infants in more than 80% of cases who exhibit impairments in the anterior chamber angle and the trabecular meshwork. Thus, a compreh...

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Bibliographic Details
Main Authors:	Muhammad, Shahid, Ahmad, Azfaralariff, Muhammad, Tufail, Nazeer Hussain, Khan, Ahmed Abdulkareem, Najm, Sabika, Firasat, Muhammad, Zubair, Shazrul, Fazry, Law, Douglas
Format:	Article
Published:	PeerJ Publishing 2022
Subjects:	QH301 Biology RE Ophthalmology
Online Access:	http://eprints.intimal.edu.my/1701/

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