Development of CRISPR-cas9 ribonucleoprotein complex platform for disruption of candidalysin in Candida albicans

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Development of CRISPR-cas9 ribonucleoprotein complex platform for disruption of candidalysin in Candida albicans

The ECE1 gene encodes the ECE1 protein, which is processed into the toxic peptide, candidalysin in Candida albicans. Candidalysin is responsible for host epithelial cell damage and activation of the host cell inflammasome pathway during C. albicans colonization and proliferation, and is the most rec...

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Bibliographic Details
Main Authors:	Ahmad, Hasna, Ramzi, Ahmad Bazli, Arzmi, Mohd Hafiz
Format:	Proceeding Paper
Language:	English English
Published:	2020
Subjects:	QR Microbiology RK Dentistry
Online Access:	http://irep.iium.edu.my/80885/ http://irep.iium.edu.my/80885/1/arcsbproceedings_frontpage_abstract.pdf http://irep.iium.edu.my/80885/2/ARCSB%20final%20slides_HASNA%20AHMAD.pdf

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