Development of CRISPR-cas9 ribonucleoprotein complex platform for disruption of candidalysin in Candida albicans
The ECE1 gene encodes the ECE1 protein, which is processed into the toxic peptide, candidalysin in Candida albicans. Candidalysin is responsible for host epithelial cell damage and activation of the host cell inflammasome pathway during C. albicans colonization and proliferation, and is the most rec...
| Main Authors: | , , |
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| Format: | Proceeding Paper |
| Language: | English English |
| Published: |
2020
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/80885/ http://irep.iium.edu.my/80885/1/arcsbproceedings_frontpage_abstract.pdf http://irep.iium.edu.my/80885/2/ARCSB%20final%20slides_HASNA%20AHMAD.pdf |