Design and synthesis of a novel mPGES-1 lead inhibitor guided by 3D-QSAR CoMFA
The search of novel mPGES-1 inhibitors has recently intensified probably due to the superior safety in comparison to existing anti-inflammatory drugs. Although two mPGES-1 inhibitors have entered clinical trials, none has yet reached the market. In this study, we performed modifications guided by 3D...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Elsevier
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/74958/ http://irep.iium.edu.my/74958/1/Kamal%20Rullah%2021.pdf http://irep.iium.edu.my/74958/7/74958_Design%20and%20synthesis%20of%20a%20novel%20_scopus.pdf http://irep.iium.edu.my/74958/13/74958_Design%20and%20synthesis%20of%20a%20novel%20mPGES-1%20lead_wos.pdf |