Significance of palpitation among hypertensive patients receiving captopril
Captopril prevent the conversion of angiotensin 1 to II by inhibiting of peptidyl dipeptide carboxy hydrolase enzyme. Captopril is an angiotensin converting enzyme (ACE) inhibitors which is the treatment of hypertension. Hundred & eight hypertensive patients taking captoprill as a tablet 25 m...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Tikrit University
2009
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/47660/ http://irep.iium.edu.my/47660/1/Significance_of_palpitation_among_hypertensive_patients_receiving_captopril.pdf |
| _version_ | 1848783182286028800 |
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| author | Marbut, Mossa M. K. Rajab, Hassan Al-Mahmood, Sinan |
| author_facet | Marbut, Mossa M. K. Rajab, Hassan Al-Mahmood, Sinan |
| author_sort | Marbut, Mossa M. |
| building | IIUM Repository |
| collection | Online Access |
| description | Captopril prevent the conversion of angiotensin 1 to II by inhibiting of peptidyl dipeptide
carboxy hydrolase enzyme. Captopril is an angiotensin converting enzyme (ACE) inhibitors which
is the treatment of hypertension. Hundred & eight hypertensive patients taking captoprill as a
tablet 25 mg twice daily (47 men & 61 women). Each patient had a complete history detailed,
physical examination, all patients were interviewed & full medical history was taken. All patients
were questioned about the presence or absence of headache, palpitation, cough, flushing, chest
pain, dysgeusia & tachycardia. Blood pressure & heart rate were measured for each patient each
visit. In hypertensive men, 29 patients out of 47 (61.7%), hypertensive patients are diagnosed as
suffering from palpitation. While in hypertensive women, 39 patients out of 61 women have
palpitation after taking captopril for 3 months (64%). In regard to serum potassium, it was
estimated in 51 hypertensive patients (27 with palpitation & 24 patients without palpitation). There
is no significant difference in regarded to serum potassium between hypertensive patients with
palpitation & hypertensive patients without palpitation. In hypertensive patients with palpitation, 9
patients out of 27 patients have hyperkalaemia (33.3%), (serum potassium more than 3 mmol/L).
In hypertensive patients without palpitation, only 3 patients out of 24 patients have hyperkalaemia
(0.125%). In hypertensive men, there are no significant differences between group with palpitation
& patients without palpitation regarding blood pressure in both systolic & diastolic. Also, there is
no significant difference regarding heart rate between group of patients with palpitation & group of
patients without palpitation. Palpitation can be attributed to one of the three main causes. The first
cause is hyperdynamic circulation which includes hypercapnia, pyrexia, thyrotoxicosis, anemia &
pregnancy. The second cause is sympathetic overdrive include panic disorders, hypoglycemia,
hypoxia, heart failure & mitral valve prolapse. While the third main cause is arrhythmias. |
| first_indexed | 2025-11-14T16:17:17Z |
| format | Article |
| id | iium-47660 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T16:17:17Z |
| publishDate | 2009 |
| publisher | Tikrit University |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-476602017-06-20T03:25:17Z http://irep.iium.edu.my/47660/ Significance of palpitation among hypertensive patients receiving captopril Marbut, Mossa M. K. Rajab, Hassan Al-Mahmood, Sinan RM300 Drugs and their action Captopril prevent the conversion of angiotensin 1 to II by inhibiting of peptidyl dipeptide carboxy hydrolase enzyme. Captopril is an angiotensin converting enzyme (ACE) inhibitors which is the treatment of hypertension. Hundred & eight hypertensive patients taking captoprill as a tablet 25 mg twice daily (47 men & 61 women). Each patient had a complete history detailed, physical examination, all patients were interviewed & full medical history was taken. All patients were questioned about the presence or absence of headache, palpitation, cough, flushing, chest pain, dysgeusia & tachycardia. Blood pressure & heart rate were measured for each patient each visit. In hypertensive men, 29 patients out of 47 (61.7%), hypertensive patients are diagnosed as suffering from palpitation. While in hypertensive women, 39 patients out of 61 women have palpitation after taking captopril for 3 months (64%). In regard to serum potassium, it was estimated in 51 hypertensive patients (27 with palpitation & 24 patients without palpitation). There is no significant difference in regarded to serum potassium between hypertensive patients with palpitation & hypertensive patients without palpitation. In hypertensive patients with palpitation, 9 patients out of 27 patients have hyperkalaemia (33.3%), (serum potassium more than 3 mmol/L). In hypertensive patients without palpitation, only 3 patients out of 24 patients have hyperkalaemia (0.125%). In hypertensive men, there are no significant differences between group with palpitation & patients without palpitation regarding blood pressure in both systolic & diastolic. Also, there is no significant difference regarding heart rate between group of patients with palpitation & group of patients without palpitation. Palpitation can be attributed to one of the three main causes. The first cause is hyperdynamic circulation which includes hypercapnia, pyrexia, thyrotoxicosis, anemia & pregnancy. The second cause is sympathetic overdrive include panic disorders, hypoglycemia, hypoxia, heart failure & mitral valve prolapse. While the third main cause is arrhythmias. Tikrit University 2009 Article PeerReviewed application/pdf en http://irep.iium.edu.my/47660/1/Significance_of_palpitation_among_hypertensive_patients_receiving_captopril.pdf Marbut, Mossa M. and K. Rajab, Hassan and Al-Mahmood, Sinan (2009) Significance of palpitation among hypertensive patients receiving captopril. Medical Journal of Tikrit, 15 (2). pp. 32-37. ISSN 1683-1813 http://www.iasj.net/iasj?func=fulltext&aId=22233 |
| spellingShingle | RM300 Drugs and their action Marbut, Mossa M. K. Rajab, Hassan Al-Mahmood, Sinan Significance of palpitation among hypertensive patients receiving captopril |
| title | Significance of palpitation among hypertensive patients receiving captopril |
| title_full | Significance of palpitation among hypertensive patients receiving captopril |
| title_fullStr | Significance of palpitation among hypertensive patients receiving captopril |
| title_full_unstemmed | Significance of palpitation among hypertensive patients receiving captopril |
| title_short | Significance of palpitation among hypertensive patients receiving captopril |
| title_sort | significance of palpitation among hypertensive patients receiving captopril |
| topic | RM300 Drugs and their action |
| url | http://irep.iium.edu.my/47660/ http://irep.iium.edu.my/47660/ http://irep.iium.edu.my/47660/1/Significance_of_palpitation_among_hypertensive_patients_receiving_captopril.pdf |