Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum
Objectives: To determine the total phenolic content, antioxidant and antimicrobial activities of the extracts from Calophyllum symingtonianum. Methods: The extracts were tested for their antioxidant activity by the DPPH radical scavenging assay and the β-carotene bleaching assay, while the anti...
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| Format: | Article |
| Language: | English |
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Coastal Life Medicine Media co., Limited
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/32204/ http://irep.iium.edu.my/32204/1/Journal_of_coastal_medicine.pdf |
| _version_ | 1848780518421692416 |
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| author | Nissad, Attoumani Darnis, Deny Susanti Bakhtiar, M. Taher |
| author_facet | Nissad, Attoumani Darnis, Deny Susanti Bakhtiar, M. Taher |
| author_sort | Nissad, Attoumani |
| building | IIUM Repository |
| collection | Online Access |
| description | Objectives: To determine the total phenolic content, antioxidant and antimicrobial activities of the extracts from Calophyllum symingtonianum.
Methods: The extracts were tested for their antioxidant activity by the DPPH radical scavenging assay and the β-carotene bleaching assay, while the antimicrobial activity was determined by disc diffusion method.
Results: All the tested extracts showed antioxidant and antimicrobial properties. The extracts showed moderate antimicrobial activity against S. aureus with zone of inhibition values of 10, 11 and 12 mm for n-hexane, DCM and methanol extracts respectively at 30 µg/disc. n-Hexane showed low antimicrobial activity against P. aeruginosa (5 mm) at 30 µg/disc. The total phenolic test showed that methanol has high phenolic content (162.25 mg GAE/g of extract) compared to the other extracts.
Conclusion: The ability of the extracts to inhibit microbial growth at a concentration of 30 µg/disc indicated the its potent antimicrobial activity.
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| first_indexed | 2025-11-14T15:34:57Z |
| format | Article |
| id | iium-32204 |
| institution | International Islamic University Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T15:34:57Z |
| publishDate | 2013 |
| publisher | Coastal Life Medicine Media co., Limited |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | iium-322042018-06-12T00:31:04Z http://irep.iium.edu.my/32204/ Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum Nissad, Attoumani Darnis, Deny Susanti Bakhtiar, M. Taher RS Pharmacy and materia medica Objectives: To determine the total phenolic content, antioxidant and antimicrobial activities of the extracts from Calophyllum symingtonianum. Methods: The extracts were tested for their antioxidant activity by the DPPH radical scavenging assay and the β-carotene bleaching assay, while the antimicrobial activity was determined by disc diffusion method. Results: All the tested extracts showed antioxidant and antimicrobial properties. The extracts showed moderate antimicrobial activity against S. aureus with zone of inhibition values of 10, 11 and 12 mm for n-hexane, DCM and methanol extracts respectively at 30 µg/disc. n-Hexane showed low antimicrobial activity against P. aeruginosa (5 mm) at 30 µg/disc. The total phenolic test showed that methanol has high phenolic content (162.25 mg GAE/g of extract) compared to the other extracts. Conclusion: The ability of the extracts to inhibit microbial growth at a concentration of 30 µg/disc indicated the its potent antimicrobial activity. Coastal Life Medicine Media co., Limited 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/32204/1/Journal_of_coastal_medicine.pdf Nissad, Attoumani and Darnis, Deny Susanti and Bakhtiar, M. Taher (2013) Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum. Journal of Coastal Life Medicine, 3 (2). pp. 1-5. ISSN 2309-6152 (O), 2309-5288 (P) http://jclmm.net/20131.htm |
| spellingShingle | RS Pharmacy and materia medica Nissad, Attoumani Darnis, Deny Susanti Bakhtiar, M. Taher Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum |
| title | Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum |
| title_full | Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum |
| title_fullStr | Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum |
| title_full_unstemmed | Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum |
| title_short | Antioxidant, antimicrobial and total phenolic contents of Calophyllum symingtonianum |
| title_sort | antioxidant, antimicrobial and total phenolic contents of calophyllum symingtonianum |
| topic | RS Pharmacy and materia medica |
| url | http://irep.iium.edu.my/32204/ http://irep.iium.edu.my/32204/ http://irep.iium.edu.my/32204/1/Journal_of_coastal_medicine.pdf |