Pharmacokinetic properties of single-dose primaquine in Papua New Guinean children: Feasibility of abbreviated high-dose regimens for radical cure of vivax malaria

Since conventional 14-day primaquine (PMQ) radical cure of vivax malaria is associated with poor compliance and as total dose, not therapy duration, determines efficacy, a preliminary pharmacokinetic study of two doses (0.5 and 1.0 mg/kg) was conducted in 28 healthy glucose-6-phosphate dehydrogenase...

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Bibliographic Details
Main Authors: Moore, Brioni, Salman, S., Benjamin, J., Page-Sharp, Madhu, Robinson, L., Waita, E., Batty, Kevin, Siba, P., Mueller, I., Davis, T., Betuela, I.
Format: Journal Article
Published: American Society for Microbiology 2014
Online Access:http://hdl.handle.net/20.500.11937/9960