Dynamics of the oncofetal ecosystem during Hepatocellular carcinoma evolution
This study uses single-cell RNA sequencing to analyse early- and late-stage hepatocellular carcinoma (HCC) patient samples, revealing an enrichment of oncofetal populations and exhausted CD8+ T cells in late-stage HCC. Cell-cell interaction analyses identified VEGFA signalling by hepatocytes and CXC...
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| Format: | Thesis |
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Curtin University
2024
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| Online Access: | http://hdl.handle.net/20.500.11937/98119 |