Exploring the Effects of the Long Noncoding RNA MIR205HG on PI3K Inhibitor Resistance in Breast Cancer
Breast cancer is a leading cause of cancer death worldwide, with nearly 21,000 cases predicted in Australia for 2024. A key driver is the PI3K pathway, often hyperactivated due to PIK3CA mutations or loss of the tumor suppressor PTEN. Resistance to PI3K inhibitors is common, but long noncoding RNAs...
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| Format: | Thesis |
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Curtin University
2025
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| Online Access: | http://hdl.handle.net/20.500.11937/97830 |