Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways

Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways

STUDY QUESTION: Is there a shared genetic or causal association of endometriosis with asthma or what biological mechanisms may underlie their potential relationships? SUMMARY ANSWER: Our results confirm a significant but non-causal association of endometriosis with asthma implicating shared genetic...

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Bibliographic Details
Main Authors: Adewuyi, Emmanuel, Mehta, D., Nyholt, D.R.
Format: Journal Article
Language:English
Published: 2022
Subjects:
GWAS
asthma
biological mechanisms
comorbidity
endometriosis
molecular genetics
sex hormones
Asthma
Endometriosis
Female
Genetic Loci
Genetic Predisposition to Disease
Genome-Wide Association Study
Gonadal Steroid Hormones
Humans
Polymorphism, Single Nucleotide
Thyroid Gland
International Endogene Consortium (IEC)
23andMe Research Team
Online Access:http://hdl.handle.net/20.500.11937/97793

Internet

http://hdl.handle.net/20.500.11937/97793

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