Shared molecular genetic mechanisms underlie endometriosis and migraine comorbidity

Shared molecular genetic mechanisms underlie endometriosis and migraine comorbidity

Observational epidemiological studies indicate that endometriosis and migraine co‐-occur within individuals more than expected by chance. However, the aetiology and biological mechanisms underlying their comorbidity remain unknown. Here we examined the relationship between endometriosis and migraine...

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Bibliographic Details
Main Authors: Adewuyi, Emmanuel, Sapkota, Y., Auta, A., Yoshihara, K., Nyegaard, M., Griffiths, L.R., Montgomery, G.W., Chasman, D.I., Nyholt, D.R.
Format: Journal Article
Language:English
Published: 2020
Subjects:
GWAS
Mendelian randomisation
causality
comorbidity
endometriosis
gene-based association study
genetic overlap
migraine
molecular genetics
pathway enrichment study
Adult
Aged
Comorbidity
Endometriosis
Female
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Linkage Disequilibrium
Mendelian Randomization Analysis
Middle Aged
Migraine Disorders
Phenotype
Phosphatidylinositol 3-Kinases
Polymorphism, Single Nucleotide
Risk Factors
Online Access:http://hdl.handle.net/20.500.11937/97784

Internet

http://hdl.handle.net/20.500.11937/97784

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